A combined team work by the visiting Australians maintained their winning spree against the hosts South Africa who lost another game in Centurion.
The Aussies amassed 492 runs with one wicket still in hand when their first innings was declared and England managed 247 for the loss of four wickets in 116 overs.
The visiting Australians are still in command of the third Test as England requires more than 200 runs with three wickets left to level the 1st Innings score.
A deadly spell in the first session of the final day from James Anderson crippled the lower order batting of Australia as England won the 1st Test at Nottingham.
The Australians followed the chase superbly but their middle order batting crumbled against the splendid bowling by the Englishmen who are anticipating a win.
A devastating knock by the debutant Ashton Agar, well supported by Phillip Hughes, put Australia on top against the hosts England on day two at Nottingham.